What is the purpose of the "2-minute rule" in using nicotine gum?

The "2-minute rule" in using nicotine gum is fundamentally about optimizing the medication's absorption and effectiveness. Chewing for 30 seconds and then resting for 2 minutes allows nicotine to be released slowly and absorbed through the buccal mucosa, rather than swallowing it, which can decrease its effectiveness. This method enhances the delivery of nicotine into the bloodstream and reduces the chance of gastrointestinal side effects that can occur if nicotine is swallowed.

The pause between chewing periods is essential, as it gives your mouth time to absorb the nicotine before chewing resumes. This technique can be crucial for individuals trying to manage their cravings for nicotine, as it helps maintain a steady level of nicotine while also preventing overconsumption. Understanding this process is crucial for anyone using nicotine replacement therapy to support their smoking cessation efforts.